Pontus Almqvist suffered an injury in training this week and will be replaced by Gabriel Strefezza up front.
Milan will set up in a 4-2-3-1 on Saturday with Samuel Chukwueze and Rade Krunic back in the starting lineup.
Poor game management after switching to a five-man defence saw Lecce concede a late comeback win by Roma last Sunday.
The Giallorossi are winless in their last six league matches and will host AC Milan,
who bounced back from last weekend’s shocking defeat to Udinese.READ MORE
with an impressive display and crucial win against PSG in the Champions League.
Milan need a win to close in on Inter, who are currently six points ahead in the league table.
Lecce, though, has been a tricky away fixture in recent seasons and the Rossoneri will need to defend well in transitions.